KPV (Ac-KPV-NH2) is a potent anti-inflammatory peptide that has shown promise in a number of disease conditions. The most active research is in the treatment of inflammatory bowel disease where the peptide has showed substantial promise. Research in wound healing also reveals that Ac-KPV-NH2 and other alpha-MSH derivatives may offer a host of benefits that speed wound healing, reduce infection, fight inflammation, and lead to better cosmetic results. Ac-KPV-NH2 and similar peptides could become mainstays not just in wound healing, but in scar reduction following surgery.